Saturday, June 27, 2009

Flu Data White versus Black


Monday, June 22, 2009

Human Evolution ~ Conjecture

What seperated us from us from the apes when we still share 98.6% of the same DNA?

Go way back, go back millenia and an ape is born, an ape that has a slight genetic birth defect. This chimp has slightly less body hair than all the other apes. This simple birth quirk has put this ape ahead of the pack.

Why?

With more exposed skin the chimp can produce more serotonin. Sunlight on the skin stimulates vitamin D production, vitamin D stimulates serotonin production. Serotonin is a powerful brain neurotransmitter. Our little chimp friend now has a brain that functions a little better than the rest of the chimps in her band. She thrives, she reproduces more frequently and over generations the brain evolves getting stronger, and working better, behavior being influenced by higher levels of serotonin. Since vitamin D affects bone growth, optimizing calcium mineralization limbs grow longer too.

Serotonin (5-hydroxytryptamine, 5-HT) is a neurotransmitter in the brain that has an enormous influence over many brain functions. It is synthesized, from the amino acid L-tryptophan, in brain neurons and stored in vesicles. Serotonin is found in three main areas of the body: the intestinal wall; large constricted blood vessels; and the central nervous system. The most widely studied effects have been those on the central nervous system. The functions of serotonin are numerous and appear to involve control of appetite, sleep, memory and learning, temperature regulation, mood, behavior (including sexual and hallucinogenic [imagination] behavior), cardiovascular function, muscle contraction, endocrine regulation, and depression
You now have a smarter monkey that breeds more and has longer limbs. More breeding brings faster evolution.

Over the eons as the genetic hair defect amplifies more and more of the body hair is lost and serum vitamin D soars, serotonin levels climb and climb further developing the brain. The ape got smarter and smarter and bred more and more prolifically and lost more and more body hair. Meanwhile the limbs continued tor grow.



Vitamin D is also critical to bone development. Higher vitamin D levels influence bone development and over time the ape grows in size.


Bioactive vitamin D or calcitriol is a steroid hormone that has long been known for its important role in regulating body levels of calcium and phosphorus, and in mineralization of bone. More recently, it has become clear that receptors for vitamin D are present in a wide variety of cells, and that this hormone has biologic effects which extend far beyond control of mineral metabolism.


Since male pattern baldness follows maternal genetic lines we could even theorize the ape with the genetic hair fault was a female.
As hominids migrated outside of the tropics, varying degrees of depigmentation evolved in order to permit UVB-induced synthesis of previtamin D3. The lighter color of female skin may be required to permit synthesis of the relatively higher amounts of vitamin D3necessary during pregnancy and lactation.

If this conjecture is to be true you would expect those races able to produce the most vitamin D would have the best performance within the human genome. Skin pigmentation has 100% correlation with vitamin D production.

The finding that skin color shows substantial correlations with life
expectancy, birth rate, and infant mortality confirms the importance of this
variable, as originally identified by Templer and Arikawa (2006).

The following would be a "forest for the trees" scenario. It is not the temperature but the lighter skin pigments found moving away from the equator;


The authors also cite a study of 20,000 skulls from 122 ethnic populations where the correlation between cranial capacity and distance from the equator was 0.62,
i.e., given that IQ is more strongly related to winter temperature than summer temperature, a plausible reason for the very strong correlation between skin color and IQ is that human populations that migrated north of the equator were selected for both lighter skin and higher IQs (the correlation between brain size and IQ is about 0.4). In this study, temperature was not an independent predictor of IQ in multiple regression analysis with IQ as the dependent variable and the other measures as independent variables.

The lighter skin color allows more UVB to penetrate the skin, produce more vitamin D, more vitamin D produces more serotonin which is a powerful neurotransmitter. And because serotonin levels drive sexual behavior you would expect higher birth rates in lighter skinned peoples.


The finding that skin color shows substantial correlations with life expectancy, birth rate, and infant mortality confirms the importance of this variable, as originally identified by Templer and Arikawa (2006).


Since chimpanzees and humans share 98.4% of the same DNA, with most of the differences being metabolic versus genetic, and the obvious difference in vitamin D production capabilities it all falls into place.

Well what about the fact that the great apes are five times stronger than humans. There is a simple answer there too. Higher serum calcium, made available by higher serum vitamin D causes muscle weakness. Even humans have a calsium ceiling and when you cross it hypercalcemia sets in with the symptom of extreme muscle weakness.

Even amoung chimps and bonobo there are adaptations tied to serum vitamin D.

If you look at Bonobo monkeys you will find they have longer legs, they are less agressive, more egalatarian, and more sexually active. Bonobo have less body hair than chimpansees.

There you have human evolution in a nutshull. We still share the same DNA and all the behavioral and physical differences are simple gene polymorphisms tied to serum vitamin D levels.

It all boils down to increased bioavailability of vitamin D and the metabolic and behavioral changes brought on by those higher levels of vitamin D which were due to body hair loss and skin pignmentation lightening.

Friday, June 19, 2009

Smoking Gun


Many of you know that they are finding many cancers are virus based, but many do not know that sunshine boosts your immune system by producing vitamin D. Vitamin D boosts your immune killer cells that kill the virus before the virus can cause cancer. Did you ever think of asking how has vitamin D changed over the years?

The answer comes in a telling question…

When was sunscreen invented and popularized? It was first invented in 1944 and popularized in the mid 1960’s. Does any more need be said than the below graph depicting the growth of lung cancer;


Keep in mind the number of people smoking decreased over these years but lung cancer continued to sky rocket.



And what does vitamin D do for the lungs?


(Vitamin D) Perhaps most importantly, it dramatically stimulates the expression of potent anti-microbial peptides, which exist in neutrophils, monocytes, natural killer cells, and in epithelial cells lining the respiratory tract where they play a major role in protecting the lung from infection.

Some will say it is all anecdotal, but all the data points in the same direction.

Check out the Inuit of the far north. They are in the midst of a vitamin D crisis of autimmune diseases. Why? Most all their vitamin D came from their traditional diet of seal, char (trout) and whale blubber, but they are changing to a westernized diet and moving away from their traditional diet.

Canadian Inuit at greatest risk of lung cancer: study
Last Updated: Monday, December 8, 2008 11:07 AM ET

Inuit in Canada's North have the highest rate of lung cancer in the world, a finding blamed largely on the popularity of cigarettes in the region, says a Canadian study.


Are you thinking yet?

Since the sun is never at the proper zenith to allow enough UVB light to hit the skin of the Inuit they relied solely on their diet for all their vitamin D needs. Animal fats and liver, particulary whale blubber is very rich in vitamin D. When the Inuit changed their diet they changed their immune system. Now autoimmune diesease is running rampage in the northern peoples.

Do you think it is simply cigarettes?

Are you willing to swallow simple spin?